Leucoderma is a hypopigmentation of the skin. Leucoderma manifests itself in the form of spots of various sizes and outlines that have a lighter color than the entire skin. The development of leucoderma is associated with a decrease in the content of melanin in the skin pigment. The reason for this is the inflammatory process in the skin, as well as nervous and endocrine disorders, since melanogenesis is regulated by the sympathetic nervous system and the pituitary hormones.
Occupational leucoderma occurs as a result of the destruction of the pigment by certain chemicals acting on the skin directly or when ingested. For example, professional leukoderma cause hydroquinone derivatives used in the manufacture of rubber products. When using rubber gloves while working, depigmented spots appear on the extensor surfaces of the hands and forearms .
A special form of leucoderma is syphilitic, which requires special treatment (see Syphilis ).
Treatment : elimination of the causes of leucoderma; with professional leucoderma, elimination of contact with chemicals that break down pigment. External treatment is required. See also Pseudo-Leukoderm .Go
Leucoderma (leukoderma; from the Greek. Leukos - white and derma - skin) - a disorder of skin pigmentation due to a decrease or disappearance of the pigment.
Most clinicians consider leucoderma a secondary hypochromic lesion of the skin. Some authors refer to the primary leucoderma syphilitic leucoderma, which is a characteristic symptom of secondary recurrent syphilis. It usually occurs no earlier than after 5-6 months. after infection and more often seen in women than in men. Leucoderma may also occur as a result of resolved skin rashes in patients with psoriasis, parapsoriasis, pink and oviformis, seborrheic eczema, trichophytosis, and favus. Under the influence of the sun's rays in normal skin, the formation of pigment increases, and this is not observed in places covered with crusts or scales (the so-called solar leukoderm). The appearance of leucoderma can also be caused by certain drugs (psoriasin, chrysarobin, etc.), under the influence of which skin pigmentation develops, while white spots remain in the lesions.
Syphilitic leucoderma is more often localized in the neck (Venus necklace), less often on the trunk and upper limbs, sometimes on the back, lower back, abdomen. White depigmented spots of the same size, 1-1.5 cm in diameter, are located close to one another in the form of a grid or lace.
There is a spotty form (Fig.) Of leucoderma, in which a small amount of white spots is located on a hyperpigmented background, and less often a marble form, in which there is no sharp contrast between the color of the spots and the surrounding skin.
False, or solar, differs from syphilitic leucoderma, in which the size of the spots corresponds to the elements of the rash and is usually different. Syphilitic leucoderma never flakes and does not cause subjective sensations.
The diagnosis of syphilitic leukoderma is confirmed by the presence of other syphilides, positive serological reactions and often specific changes in the cerebrospinal fluid (see Syphilis, serological studies).
Treatment - antisyphilitic, followed by careful observation of patients. Secondary leucodermas, developing ate the above dermatoses, usually regress without any treatment.
Syphilitic leucoderma (spotted form).