Lymphoma (synonym: lymphocytoma, lymphadenoma) is a conditional collective term that characterizes the foci of lymphoid tissue neoplasm, both in the lymph nodes and in any other organs and tissues.
Lymphomas are divided into benign and malignant. The latter are true neoplasms of lymphoid tissue, mainly of systemic order. However, the term “lymphoma” also refers to the formations that have arisen as a result of reactive processes (the so-called simple lymphoma, lymphoma simplex).
Simple lymphoma (Fig.) Is a limited infiltration of lymphoid cells with more or less pronounced light multiplication centers, morphologically identical lymphatic follicles. Its origin is associated with: 1) a chronic inflammatory process in organs and tissues; 2) with the processes of regeneration of lymphoid tissue; 3) with symptoms of lymph stagnation.
A number of researchers believe that the formation of lymphomas in tissues or organs is a morphological expression of the degree of immunological intensity of an organism.
Benign lymphoma is an intermediate form between simple and malignant lymphoma and is characterized by neoplasm of lymphoid tissue in lymph nodes (usually cervical, submandibular, axillary, inguinal). These neoplasms are knotty, dense to the touch, grow very slowly, clinically asymptomatic. The origin of benign lymphoma is associated with chronic inflammation. Histological examination of benign lymphoma is a simple lymphoma in the lung in chronic nonspecific pneumonia.
the normal structure of the lymph nodes with slightly enlarged follicles, with large bright centers of reproduction. The sinuses of the lymph nodes do not differ, their place is taken up by hyperplastic lymphoid tissue, which brings this type of lymphomas closer to tumors.
Malignant lymphoma is observed in patients with systemic diseases of the hematopoietic system, it can be common and limited (see Leukemia, Giant lymphoma, Lymphogranulomatosis).