Lobelin (Lobelinum) is a breath stimulant. In medical practice, lobeline hydrochloride is used - Lobelinum hydrochloricum, Lobelini hydrochloridum. The stimulating effect on respiration is mainly due to the excitation of the n-cholinergic receptors of the synokartide zone. Used to stimulate respiration, in particular when reflex apnea. Lobeline is administered intravenously slowly at 0.3-0.5 ml of 1% solution. Sometimes injected into a muscle. Higher doses: in a single vein - 0.005 g, daily - 0.01 g, in a single muscle - 0.01 g, daily - 0.02 g. Release forms:
powder ( list A ) and ampoules of 1 ml of 1% solution ( list B ). See also Stimulants of nervous activity .
Lobelin (Lobelinurn) - breath stimulator, alkaloid from the plant Lobelia inflate; in medical practice it is used in the form of 2- (β-oxyphenethyl) -1-methyl-6-phenacylpiperidine hydrochloride. The action of lobeline is associated mainly with the excitation of the carotid glomeruli, as well as with the effect on the respiratory center. Lobeline is used to stop or weaken the breathing, mainly of a reflex nature, in the absence of significant disturbances of the cardiovascular system, with asphyxiation of the newborn. Lobelin can be used for diagnostic purposes to determine the speed of blood flow. Lobeline is introduced into the vein and intramuscularly in a dose of 0.3–0.5 ml of a 1% solution for adults; children - 0.1 - 0.3 ml of 1% solution. Form release: powders (list A) and ampoules of 1 ml of 1% solution (list B). See also Stimulants of nervous activity.