Luteoma - is a luteal cell tumor of the ovary, occurs in women aged 15-75 years. It is formed, probably, by luteinization of tumors of granular cells or tech-cells. Tumor cells secrete estrogen and progesterone, as a result of which secretory and pre-cidicular changes of the uterine mucosa are observed. Enhanced production of androgens and ketosteroids is accompanied by virilization. As a result, girls develop precocious puberty with male features. In adults, virilization, depression , irritability, acne, male-pattern baldness, hirsutism, hypertrophy of the mammary glands and uterus, a decrease in sexual desire occur. Amenorrhea alternates with menorrhagia.
The diagnosis is made on the basis of microscopic examination.
Treatment is prompt.