Reticulosarcoma is a malignant neoplasm that originates from lymphoreticular tissue and consists of large, slightly differentiated reticular cells that gradually replace the tissue of the lymph nodes.
Sarcoma , which develops from undifferentiated reticular cells similar to lymphoid cells, was designated by the term "lymphosarcoma". Currently, these sarcomas are referred to as reticulosarcomas. The term "lymphosarcoma" goes out of use. The duration of the disease is on average about 3 years, men get sick more often. Lymph nodes of the neck, axillary regions, mediastinum , retroperitoneal space, as well as soft tissues, skin, abdominal organs, bones, etc., are affected. Isolated lesions of the stomach, intestines, tonsils, and nasopharynx are also observed, but in the future the disease progresses almost always generalization of the process. With reticulosarcomas, multiple packets of lymph nodes are formed, dense large sedentary tumors. Clinical manifestations of the disease are very diverse and depend on the prevalence of the lesion and the multiplicity of its localization.
The most reliable diagnostic method is a cytological examination of the punctate of the altered lymph node or a histological study of a piece of the tumor. When treating patients, chemotherapy is used ( cyclophosphamide , chlorbutin , etc.). Radiation treatment with a small lesion also gives remission . In case of local lesions of the stomach or intestine, surgical removal of the primary focus is indicated; it often leads to a lasting improvement. Comprehensive treatment is recommended in a hospital setting. Patients with suspected reticulosarcoma should be urgently referred to an oncologic hospital.