Takayasu syndrome (a synonym for the disease of lack of pulse) is a disease caused by the obliterating arteritis of large vessels moving away from the aorta. Etiology and pathogenesis are not clear. More common in young women. Symptoms: weakness of the muscles of the upper half of the body, headaches and dizziness, a disturbance of vision, increasing in standing position, memory and consciousness disorders . Hands are pale, cold. On one of the radial arteries, occasionally on both, the pulse is not palpated and the arterial pressure is not determined. Duration of the disease is from 2 to 14 years. The outlook is unfavorable. For treatment use hormonal ( prednisolone , etc.) and antihistamine (diphenhydramine, pipolfen, etc.) drugs, butadione, amidopirin . They perform reconstructive (reconstructive) operations on the affected vessels - replacing them with vascular prostheses.