Trofedema (a synonym for Meyzh disease) is a rare disease, manifested by a limited periodically increasing edema of body parts. Occurs in adults of both sexes.
Etiology has not been established, but in some cases it is associated with hereditary factors, intoxication, traumatic brain injury, endocrine disorders, etc.
Trofedema is a chronic edema, sometimes sharply increasing, at the same time different parts of the body, of limited size (from 4 to 10 cm 2 ), mainly on the face (mainly on the lips) and lower limbs. Edema is dense, sometimes symmetrical, increases dramatically in the course of several hours or days, after pressing a finger on it does not remain. The duration and frequency of crises are varied: they occur once a week, a month, a year, and even less.
In the area of edema, the compaction of the tissues sometimes occurs rather quickly, and in some cases the compaction is formed over the years, assuming the character of individual nodes.
When edema occurs, general weakness usually occurs, body temperature rises, a headache appears, in some cases such crises are tolerated by patients without any special complaints. In some patients, seizures are accompanied by edema of the internal organs (respiratory tract, gastrointestinal tract, etc.), as well as the brain.
Milofya's disease, manifested by extensive chronic edema of one or both legs, cannot be attributed to the trophedema; the disease is predominantly inborn.
Forecast . Unlike angioedema, trofedematous edema does not completely disappear. The disease occurs chronically, with the localization of edema on the face leads to disfigurement.
Patients should be treated in a neurological hospital. They prescribe anti-infective, dehydration, fortifying and sedatives , multivitamins, vitamin B15 . Apply corticosteroid drugs and anabolic steroids (nerobol, etc.). In cases of severe disfigurement - plastic surgery .