Dystrophy of cells and tissues is a disorder of nutrition and metabolism in cells and tissues, causing a violation of their structure and function.
Dystrophy of cells and tissues can occur under the influence of various causes: impaired blood supply to the organ, in endocrine system diseases, temperature shifts, under the influence of toxic substances, toxins produced in the body in infectious diseases, etc.
Dystrophy of cells and tissues for the most part is transient, and when the cause of the dystrophy is removed, the normal state of the tissue is restored. The progression of degeneration of cells and tissues can lead to necrosis (see).
Distinguish between protein, fat, carbohydrate, watering, mineral dystrophy. Among proteinaceous dystrophies the most important are amyloidosis (see), hyalinosis (see), granular dystrophy of parenchymatous organs. In case of fatty dystrophy of cells and tissues, there is either an increase in the content of fatty substances in cells, where they exist and are normal, or they appear where they are normally not found. Water drainage (hydropic) dystrophy of cells and tissues is characterized by the appearance of water bubbles (vacuoles) in the cells. In carbohydrate dystrophies of cells and tissues, glycogen (see) disappears from cells where it is contained as the main energetic material (for example, from cells of the heart muscle), or it appears in the cytoplasm or cell nuclei, which normally do not contain it (for example, in liver cells in diabetes). Mineral dystrophies - see Calcinosis.